KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K7
All Species:
22.42
Human Site:
Y143
Identified Species:
44.85
UniProt:
O43318
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43318
NP_003179.1
606
67196
Y143
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
Chimpanzee
Pan troglodytes
XP_001160138
472
51727
E37
E
I
D
Y
K
E
I
E
V
E
E
V
V
G
R
Rhesus Macaque
Macaca mulatta
XP_001099744
609
67549
Y143
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q62073
579
64209
M131
Y
Y
T
A
A
H
A
M
S
W
C
L
Q
C
S
Rat
Rattus norvegicus
P0C8E4
606
67182
Y143
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507638
595
66386
Y130
Q
C
S
Q
G
V
A
Y
L
H
S
M
Q
P
K
Chicken
Gallus gallus
XP_001233491
604
67342
Y133
Q
C
S
Q
G
V
A
Y
L
H
S
M
K
P
K
Frog
Xenopus laevis
Q7T2V3
1005
111856
E233
G
M
T
Y
L
H
N
E
A
I
V
P
I
I
H
Zebra Danio
Brachydanio rerio
NP_001018586
544
61104
T108
A
E
P
L
P
H
Y
T
A
S
H
A
M
S
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3Q6
678
75656
Y127
Q
C
A
E
G
L
A
Y
L
H
A
M
T
P
K
Honey Bee
Apis mellifera
XP_397248
510
58111
I75
S
R
V
I
H
P
N
I
V
K
L
Y
G
A
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795629
463
51420
G28
F
E
K
V
V
G
K
G
A
F
G
V
V
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
99.5
N.A.
N.A.
95
99
N.A.
91.4
91.7
21.9
70.6
N.A.
34.5
41.4
N.A.
39.9
Protein Similarity:
100
75.7
99.5
N.A.
N.A.
95
99.3
N.A.
93.7
93.7
35.7
77.8
N.A.
52.2
58.7
N.A.
51.4
P-Site Identity:
100
0
100
N.A.
N.A.
13.3
100
N.A.
100
93.3
0
0
N.A.
66.6
0
N.A.
6.6
P-Site Similarity:
100
26.6
100
N.A.
N.A.
26.6
100
N.A.
100
100
6.6
0
N.A.
93.3
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
9
9
0
59
0
25
0
9
9
0
9
0
% A
% Cys:
0
50
0
0
0
0
0
0
0
0
9
0
0
9
9
% C
% Asp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
17
0
9
0
9
0
17
0
9
9
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
9
0
0
0
50
9
0
9
0
0
9
0
9
9
0
% G
% His:
0
0
0
0
9
25
0
0
0
50
9
0
0
0
9
% H
% Ile:
0
9
0
9
0
0
9
9
0
9
0
0
9
9
0
% I
% Lys:
0
0
9
0
9
0
9
0
0
9
0
0
9
0
59
% K
% Leu:
0
0
0
9
9
9
0
0
50
0
9
9
0
0
0
% L
% Met:
0
9
0
0
0
0
0
9
0
0
0
50
9
0
0
% M
% Asn:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
9
9
0
0
0
0
0
9
0
50
0
% P
% Gln:
50
0
0
42
0
0
0
0
0
0
0
0
42
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
9
0
42
0
0
0
0
0
9
9
42
0
0
17
9
% S
% Thr:
0
0
17
0
0
0
0
9
0
0
0
0
9
0
0
% T
% Val:
0
0
9
9
9
42
0
0
17
0
9
17
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% W
% Tyr:
9
9
0
17
0
0
9
50
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _